Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet

K. Dhami, D.A. Malyshev, P. Ordoukhanian, T. Kubelka, M. Hocek, F.E. Romesberg, Nucleic Acids Res (2014) 42:10235-10244.
pubpic2014dhamiWe report a PCR-based screen to identify promising unnatural base pairs from a library of 111 unnatural nucleotides (~6,000 candidate base pairs).

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