Carbon-deuterium bonds as non-perturbative infrared probes of protein dynamics, electrostatics, heterogeneity, and folding

J. Zimmermann, F.E. Romesberg, Methods Mol. Biol. (2014) 1084:101-19.
pubpic2014zimmermannWe describe the experimental procedures required to use C-D bonds and FT IR spectroscopy to characterize protein dynamics, structural and electrostatic heterogeneity, ligand binding, and folding.

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