Phosphatases, DNA Damage Checkpoints and Checkpoint Deactivation

J. Heideker, E.T. Lis, F.E. Romesberg, Cell Cycle (2007) 6:3058-3064.
pubpic2007heidekerWe review progress toward understanding the functions of phosphatases in checkpoint deactivation in S. cerevisiae, focusing on the non-redundant roles of the type 2A phosphatase Pph3 and the PP2C phosphatases Ptc2 and Ptc3 in the deactivation of Rad53.