The complete and SOS-mediated response of Staphylococcus aureus to the antibiotic ciprofloxacin

R.T. Cirz, M.B. Jones, N.A. Gingles, T.D. Minogue, B. Jarrahi, S.N. Peterson, F.E. Romesberg, J. Bacteriol. (2007) 189:531-539.
pubpic2006dcirzWe characterize the global transcriptional response of S. aureus to ciprofloxacin and find that the drug induces prophage mobilization as well as significant alterations in metabolism, most notably the up-regulation of the tricarboxylic acid cycle.[Download Supporting Information]