Optimization of unnatural base pair packing for polymerase recognition

S. Matsuda, A.A. Henry, F.E. Romesberg, J. Am. Chem. Soc. (2006) 128:6369-6375.
pubpic2006matsudaWe report the characterization of polymerase-mediated replication of unnatural base pairs formed between nucleotides bearing simple methyl-substituted phenyl ring nucleobase analogs.

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