Induction and inhibition of ciprofloxacin resistance-conferring mutations in hypermutator bacteria

R.T. Cirz, F.E. Romesberg, Antimicrob. Agents Chemother. (2006) 50:220-225.
pubpic2006cirzWe show that LexA cleavage and polymerase derepression are required for the evolution of clinically significant resistance in MMR-defective E. coli.

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