Inhibition of mutation and combating the evolution of antibiotic resistance

R.T. Cirz, J.K. Chin, D.R. Andes, V. de Crécy-Lagard, W.A. Craig, F.E. Romesberg, PLoS Biol. (2005) 3:e176.
pubpic2005cirzThe results presented herein indicate that the inhibition of mutation could serve as a novel therapeutic strategy to combat the evolution of antibiotic resistance. Read more in C&EN, C&EN 2005 highlights, and Nat. Rev. Genetics, or listen to Sci. Am. Science Talk.